I've recently been doing some tuning for various customers on Linux. While I've focused primarily on zLinux in the past, this particular tip is for Linux on AMD Operton. But, I thought it was worth noting an I hope that if this matches your particular environment, you also find it helpful
Slower OLTP workload performance running on Linux RHEL on AMD, when HPET (high precision event timer) is disabled in the operating system.
The details of this technote can be found here:
Continued and Happy Tuning...